First approved by the FDA in 2006, JUVÉDERM® ULTRA PLUS XC corrects moderate to severe facial wrinkles and folds, such as the parentheses lines or “smile/laugh lines” around the nose and mouth, also known as nasolabial folds. JUVÉDERM® ULTRA PLUS XC is injected into areas of facial tissue where moderate to severe facial wrinkles and folds occur to temporarily add volume to the skin, which may give the appearance of a smoother surface.